This article explores the growing threat of and the legal response to microplastic pollution. Microplastics—plastic particles smaller than five millimeters in size—are pervasive, persistent, and chemically diverse, making them particularly difficult to regulate using existing environmental statutes. Federal approaches, such as the Clean Water Act and the Toxic Substances Control Act, offer limited relief. At the same time, macro-scale proposals like the Break Free from Plastic Pollution Act and a Global Plastic Treaty remain stalled. In response, this article advocates for “micro-solutions”—targeted, state and local interventions that address microplastic pollution across the plastic lifecycle. These include targeted product bans, labeling requirements, and design modifications. By highlighting these bottom-up strategies, some of which prioritize health concerns, the article provides a roadmap for meaningful progress and practical solutions in the absence of sweeping federal or international reform.